Isolated left ventricular noncompaction (LVNC) is a genetic cardiomyopathy characterized by prominent ventricular trabeculations\nand deep intertrabecular recesses, or sinusoids, in communication with the left ventricular cavity. The low prevalence of patients\nwith this cardiomyopathy presents a unique challenge for large, prospective trials to assess its pathogenesis, management, and\noutcomes. In this paper we review the embryology and genetics of LVNC, the diagnostic approach, and propose a management\napproach based on the current literature available.
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